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Clustering of vomeronasal receptor genes is required for transcriptional stability but not for choice

Rodents perceive pheromones via vomeronasal receptors encoded by highly evolutionarily dynamic Vr and Fpr gene superfamilies. We report here that high numbers of V1r pseudogenes are scattered in mammalian genomes, contrasting with the clustered organization of functional V1r and Fpr genes. We also f...

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Detalles Bibliográficos
Autores principales:	Dietschi, Quentin, Tuberosa, Joël, Fodoulian, Leon, Boillat, Madlaina, Kan, Chenda, Codourey, Julien, Pauli, Véronique, Feinstein, Paul, Carleton, Alan, Rodriguez, Ivan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668312/ https://www.ncbi.nlm.nih.gov/pubmed/36383665 http://dx.doi.org/10.1126/sciadv.abn7450

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