A prebiotic diet modulates microglial states and motor deficits in α-synuclein overexpressing mice

Parkinson’s disease (PD) is a movement disorder characterized by neuroinflammation, α-synuclein pathology, and neurodegeneration. Most cases of PD are non-hereditary, suggesting a strong role for environmental factors, and it has been speculated that disease may originate in peripheral tissues such...

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Detalles Bibliográficos
Autores principales: Abdel-Haq, Reem, Schlachetzki, Johannes CM, Boktor, Joseph C, Cantu-Jungles, Thaisa M, Thron, Taren, Zhang, Mengying, Bostick, John W, Khazaei, Tahmineh, Chilakala, Sujatha, Morais, Livia H, Humphrey, Greg, Keshavarzian, Ali, Katz, Jonathan E, Thomson, Matthew, Knight, Rob, Gradinaru, Viviana, Hamaker, Bruce R, Glass, Christopher K, Mazmanian, Sarkis K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Microbiology and Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668333/
https://www.ncbi.nlm.nih.gov/pubmed/36346385
http://dx.doi.org/10.7554/eLife.81453

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