The CIC-ERF co-deletion underlies fusion-independent activation of ETS family member, ETV1, to drive prostate cancer progression

Human prostate cancer can result from chromosomal rearrangements that lead to aberrant ETS gene expression. The mechanisms that lead to fusion-independent ETS factor upregulation and prostate oncogenesis remain relatively unknown. Here, we show that two neighboring transcription factors, Capicua (CI...

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Detalles Bibliográficos
Autores principales: Gupta, Nehal, Song, Hanbing, Wu, Wei, Ponce, Rovingaile K, Lin, Yone K, Kim, Ji Won, Small, Eric J, Feng, Felix Y, Huang, Franklin W, Okimoto, Ross A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668335/
https://www.ncbi.nlm.nih.gov/pubmed/36383412
http://dx.doi.org/10.7554/eLife.77072

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