Evaluation of the influence of genetic variants in Cereblon gene on the response to the treatment of erythema nodosum leprosum with thalidomide

BACKGROUND: Erythema nodosum leprosum (ENL) is an acute and systemic inflammatory reaction of leprosy characterised by painful nodules and involvement of various organs. Thalidomide is an immunomodulatory and anti-inflammatory drug currently used to treat this condition. Cereblon (CRBN) protein is t...

Descripción completa

Detalles Bibliográficos
Autores principales: Costa, Perpétua do Socorro Silva, Maciel-Fiuza, Miriãn Ferrão, Kowalski, Thayne Woycinck, Fraga, Lucas Rosa, Feira, Mariléa Furtado, Camargo, Luís Marcelo Aranha, Caldoncelli, Daniele Iop de Oliveira, Silveira, Maria Irismar da Silva, Schuler-Faccini, Lavínia, Vianna, Fernanda Sales Luiz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668341/
https://www.ncbi.nlm.nih.gov/pubmed/36383784
http://dx.doi.org/10.1590/0074-02760220039

Ejemplares similares

Ejemplares similares