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Salivary Cortisol and Sustained Auditory Attention in Children with and without Cleft Lip and Palate

Introduction  Cortisol is a hormone involved in the response to stress. Attention is a function that can change due to exposure to stress. Objectives  To verify the correlation between the level of salivary cortisol and sustained auditory attention in children with cleft lip and palate, as well as t...

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Autores principales: Fernandes, Viviane Mendes, Mondelli, Maria Fernanda Capoani Garcia, José, Maria Renata, Gomide, Márcia Ribeiro, Lauris, José Roberto Pereira, Feniman, Mariza Ribeiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Revinter Publicações Ltda. 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668409/
https://www.ncbi.nlm.nih.gov/pubmed/36405466
http://dx.doi.org/10.1055/s-0041-1735130
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author Fernandes, Viviane Mendes
Mondelli, Maria Fernanda Capoani Garcia
José, Maria Renata
Gomide, Márcia Ribeiro
Lauris, José Roberto Pereira
Feniman, Mariza Ribeiro
author_facet Fernandes, Viviane Mendes
Mondelli, Maria Fernanda Capoani Garcia
José, Maria Renata
Gomide, Márcia Ribeiro
Lauris, José Roberto Pereira
Feniman, Mariza Ribeiro
author_sort Fernandes, Viviane Mendes
collection PubMed
description Introduction  Cortisol is a hormone involved in the response to stress. Attention is a function that can change due to exposure to stress. Objectives  To verify the correlation between the level of salivary cortisol and sustained auditory attention in children with cleft lip and palate, as well as to compare the results of the variables analyzed between female and male patients. Methods  In total, 103 children aged 6 to 11 years, were divided into 2 groups: those with cleft lip and palate (experimental group, EG; n  = 69) and the control group (CG; n  = 34). The Sustained Auditory Attention Ability Test (SAAAT) and salivary cortisol levels, measured by an enzyme immunoassay kit (Salimetrics, Stage College, PA, US), were calculated and compared regarding the two groups. The statistical tests used were the Mann-Whitney test and the Spearman correlation. Results  The median level of salivary cortisol was of 0.03615 µl/dL and 0.18000 µl/dL respectively for the EG and CG, with a significant difference between the groups ( p  = 0.000). Absence of statistical significance (total error score = 0.656; vigilance decrement = 0.051) was observed the for SAAAT among the EG (median total error score = 12.00; 25th percentile [25%] = 7.00; 75th percentile [75%] = 21.00; and vigilance decrement = 1.00; 25% = 0.00; 75% = 2.50) and the CG (median total error score = 12.00; 25% = 6.00; 75% = 24.00; and vigilance decrement = 0.00; 25% = -1.00; 75% = 2.00). Conclusion  All children had median levels of salivary cortisol and scores for sustained auditory attention within normal parameters. A significant correlation between the level of salivary cortisol and the ability to sustain auditory attention was observed in children without cleft lip and palate. There were no differences regarding the SAAAT and salivary cortisol between female and male patients.
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spelling pubmed-96684092022-11-17 Salivary Cortisol and Sustained Auditory Attention in Children with and without Cleft Lip and Palate Fernandes, Viviane Mendes Mondelli, Maria Fernanda Capoani Garcia José, Maria Renata Gomide, Márcia Ribeiro Lauris, José Roberto Pereira Feniman, Mariza Ribeiro Int Arch Otorhinolaryngol Introduction  Cortisol is a hormone involved in the response to stress. Attention is a function that can change due to exposure to stress. Objectives  To verify the correlation between the level of salivary cortisol and sustained auditory attention in children with cleft lip and palate, as well as to compare the results of the variables analyzed between female and male patients. Methods  In total, 103 children aged 6 to 11 years, were divided into 2 groups: those with cleft lip and palate (experimental group, EG; n  = 69) and the control group (CG; n  = 34). The Sustained Auditory Attention Ability Test (SAAAT) and salivary cortisol levels, measured by an enzyme immunoassay kit (Salimetrics, Stage College, PA, US), were calculated and compared regarding the two groups. The statistical tests used were the Mann-Whitney test and the Spearman correlation. Results  The median level of salivary cortisol was of 0.03615 µl/dL and 0.18000 µl/dL respectively for the EG and CG, with a significant difference between the groups ( p  = 0.000). Absence of statistical significance (total error score = 0.656; vigilance decrement = 0.051) was observed the for SAAAT among the EG (median total error score = 12.00; 25th percentile [25%] = 7.00; 75th percentile [75%] = 21.00; and vigilance decrement = 1.00; 25% = 0.00; 75% = 2.50) and the CG (median total error score = 12.00; 25% = 6.00; 75% = 24.00; and vigilance decrement = 0.00; 25% = -1.00; 75% = 2.00). Conclusion  All children had median levels of salivary cortisol and scores for sustained auditory attention within normal parameters. A significant correlation between the level of salivary cortisol and the ability to sustain auditory attention was observed in children without cleft lip and palate. There were no differences regarding the SAAAT and salivary cortisol between female and male patients. Thieme Revinter Publicações Ltda. 2022-02-09 /pmc/articles/PMC9668409/ /pubmed/36405466 http://dx.doi.org/10.1055/s-0041-1735130 Text en Fundação Otorrinolaringologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Fernandes, Viviane Mendes
Mondelli, Maria Fernanda Capoani Garcia
José, Maria Renata
Gomide, Márcia Ribeiro
Lauris, José Roberto Pereira
Feniman, Mariza Ribeiro
Salivary Cortisol and Sustained Auditory Attention in Children with and without Cleft Lip and Palate
title Salivary Cortisol and Sustained Auditory Attention in Children with and without Cleft Lip and Palate
title_full Salivary Cortisol and Sustained Auditory Attention in Children with and without Cleft Lip and Palate
title_fullStr Salivary Cortisol and Sustained Auditory Attention in Children with and without Cleft Lip and Palate
title_full_unstemmed Salivary Cortisol and Sustained Auditory Attention in Children with and without Cleft Lip and Palate
title_short Salivary Cortisol and Sustained Auditory Attention in Children with and without Cleft Lip and Palate
title_sort salivary cortisol and sustained auditory attention in children with and without cleft lip and palate
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668409/
https://www.ncbi.nlm.nih.gov/pubmed/36405466
http://dx.doi.org/10.1055/s-0041-1735130
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