Cargando…

Baicalin Mitigates the Neuroinflammation through the TLR4/MyD88/NF-κB and MAPK Pathways in LPS-Stimulated BV-2 Microglia

Baicalin (BA) is a major flavone from Scutellaria baicalensis Georgi and has showed significant curative effects in Parkinson's and Alzheimer's diseases. In the present study, we investigated the effects of BA on antineuroinflammation and related signaling cascade in lipopolysaccharide- (L...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Baojing, Wang, Mingming, Chen, Shuai, Li, Manping, Zeng, Jing, Wu, Saichun, Tu, Yuanqing, Li, Yanping, Zhang, Rongping, Huang, Feng, Tong, Xiaoyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668451/ https://www.ncbi.nlm.nih.gov/pubmed/36408278 http://dx.doi.org/10.1155/2022/3263446

Ejemplares similares

Phyllanthus amarus prevents LPS-mediated BV2 microglial activation via MyD88 and NF-κB signaling pathways
por: Ismail, Elysha Nur, et al.
Publicado: (2020)

MyD88 and beyond: a perspective on MyD88-targeted therapeutic approach for modulation of host immunity
por: Saikh, Kamal U.
Publicado: (2021)

Schisandrin B Attenuates Diabetic Cardiomyopathy by Targeting MyD88 and Inhibiting MyD88‐Dependent Inflammation
por: Luo, Wu, et al.
Publicado: (2022)

Soyasaponins reduce inflammation by downregulating MyD88 expression and suppressing the recruitments of TLR4 and MyD88 into lipid rafts
por: Chen, Junbin, et al.
Publicado: (2020)

A MyD88 meddles with survival
por: Bashyam, Hema
Publicado: (2007)

Role of MyD88 in Adenovirus Keratitis
por: Zhou, Xiaohong, et al.
Publicado: (2016)

Heparin alleviates LPS-induced endothelial injury by regulating the TLR4/MyD88 signaling pathway
por: Liu, Wenxun, et al.
Publicado: (2021)

Ishige okamurae Attenuates Neuroinflammation and Cognitive Deficits in Mice Intracerebroventricularly Injected with LPS via Regulating TLR-4/MyD88-Dependent Pathways
por: Kwon, Oh-Yun, et al.
Publicado: (2022)

Ganoderic Acid A Attenuates LPS-Induced Neuroinflammation in BV2 Microglia by Activating Farnesoid X Receptor
por: Jia, Yue, et al.
Publicado: (2021)

MyD88 deficiency aggravates the severity of acute pancreatitis by promoting MyD88-independent TRIF pathway-mediated necrosis
por: Yang, Du-Jiang, et al.
Publicado: (2022)

Rhein Suppresses Neuroinflammation via Multiple Signaling Pathways in LPS-Stimulated BV2 Microglia Cells
por: Zheng, Piao, et al.
Publicado: (2020)

Baicalin Ameliorates Cognitive Impairment and Protects Microglia from LPS-Induced Neuroinflammation via the SIRT1/HMGB1 Pathway
por: Li, Yue, et al.
Publicado: (2020)

Identification and Function of Myeloid Differentiation Factor 88 (MyD88) in Litopenaeus vannamei
por: Zhang, Shuang, et al.
Publicado: (2012)

MyD88 contribution to ocular surface homeostasis
por: Reins, Rose Y., et al.
Publicado: (2017)

Mechanism of MyD88S mediated signal termination
por: Pustelny, Katarzyna, et al.
Publicado: (2022)

A Novel Kindred with MyD88 Deficiency
por: Bucciol, Giorgia, et al.
Publicado: (2022)

Lipopolysaccharide-induced NF-κB nuclear translocation is primarily dependent on MyD88, but TNFα expression requires TRIF and MyD88
por: Sakai, Jiro, et al.
Publicado: (2017)

Mucus clearance, MyD88-dependent and MyD88-independent immunity modulate lung susceptibility to spontaneous bacterial infection and inflammation
por: Livraghi-Butrico, Alessandra, et al.
Publicado: (2012)

Fucoxanthin attenuates LPS-induced acute lung injury via inhibition of the TLR4/MyD88 signaling axis
por: Li, Xiaoling, et al.
Publicado: (2020)

Maternal B Cell-Intrinsic MyD88 Signaling Mediates LPS-Driven Intrauterine Fetal Death
por: Busse, Mandy, et al.
Publicado: (2021)

Dexmedetomidine Attenuates Neuroinflammation In LPS-Stimulated BV2 Microglia Cells Through Upregulation Of miR-340
por: Bao, Yang, et al.
Publicado: (2019)

Tacrolimus alleviates LPS‐induced AKI by inhibiting TLR4/MyD88/NF‐κB signalling in mice
por: Hu, Xueqing, et al.
Publicado: (2021)

Ramulus Cinnamomi extract attenuates neuroinflammatory responses via downregulating TLR4/MyD88 signaling pathway in BV2 cells
por: Yang, Huan, et al.
Publicado: (2017)

MyD88 Polymorphisms and Association with Susceptibility to Salmonella Pullorum
por: Liu, Xian-Qing, et al.
Publicado: (2015)

Lys694Arg polymorphism leads to blunted responses to LPS by interfering TLR4 with recruitment of MyD88
por: Yang, Yajie, et al.
Publicado: (2020)

Amentoflavone Exerts Anti-Neuroinflammatory Effects by Inhibiting TLR4/MyD88/NF-κB and Activating Nrf2/HO-1 Pathway in Lipopolysaccharide-Induced BV2 Microglia
por: Rong, Shikuo, et al.
Publicado: (2022)

From monogenic lupus to TLR7/MyD88-targeted therapy
por: Wang, Min, et al.
Publicado: (2022)

Anti-Inflammatory Activity of Bee Venom in BV2 Microglial Cells: Mediation of MyD88-Dependent NF-κB Signaling Pathway
por: Im, Eun Ju, et al.
Publicado: (2016)

MyD88 Mediates Colitis- and RANKL-Induced Microfold Cell Differentiation
por: Li, Yang, et al.
Publicado: (2021)

Myeloid Differentiation Factor 88 (MyD88)-Deficiency Increases Risk of Diabetes in Mice
por: Hosoi, Toru, et al.
Publicado: (2010)

Povidone iodine suppresses LPS-induced inflammation by inhibiting TLR4/MyD88 formation in airway epithelial cells
por: Lee, Seung Hoon, et al.
Publicado: (2022)

MyD88 and TLR4 Expression in Epithelial Ovarian Cancer
por: Block, Matthew S., et al.
Publicado: (2018)

TLR signaling adaptor protein MyD88 in primary sensory neurons contributes to persistent inflammatory and neuropathic pain and neuroinflammation
por: Liu, Xing-Jun, et al.
Publicado: (2016)

Data-Driven Modeling Identifies TIRAP-Independent MyD88 Activation Complex and Myddosome Assembly Strategy in LPS/TLR4 Signaling
por: Li, Xiang, et al.
Publicado: (2020)

MyD88 predicts chemoresistance to paclitaxel in epithelial ovarian cancer
por: Silasi, Dan-Arin, et al.
Publicado: (2007)

Alternative activation of macrophages by filarial nematodes is MyD88-independent
por: Mylonas, Katie J., et al.
Publicado: (2013)

MyD88-Dependent Pathways in Leukocytes Affect the Retina in Diabetes
por: Tang, Jie, et al.
Publicado: (2013)

MyD88: a central player in innate immune signaling
por: Deguine, Jacques, et al.
Publicado: (2014)

MyD88 signalling is critical in the development of pancreatic cancer cachexia
por: Zhu, Xinxia, et al.
Publicado: (2019)

Inflammatory Role of TLR-MyD88 Signaling in Multiple Sclerosis
por: Zheng, Chao, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_qpcv97r75nsbgu0unsckis9ugh