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Directed evolution of the fusion enzyme for improving astaxanthin biosynthesis in Saccharomyces cerevisiae

The accumulation of the intermediate zeaxanthin and canthaxanthin in the astaxanthin biosynthesis pathway catalyzed by β-carotene hydroxylase (crtZ) and β-carotene ketolase (crtW) decreases the content of the astaxanthin. Here, we exploited directed evolution of the fusion of crtZ and crtW for impro...

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Detalles Bibliográficos
Autores principales: Ding, Yong-Wen, Lu, Chuan-Zhen, Zheng, Yan, Ma, Han-Zhang, Jin, Jin, Jia, Bin, Yuan, Ying-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668533/
https://www.ncbi.nlm.nih.gov/pubmed/36408203
http://dx.doi.org/10.1016/j.synbio.2022.10.005

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