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The spatio-temporal relationship between white matter lesion volume changes and brain atrophy in clinically isolated syndrome and early multiple sclerosis

BACKGROUND: White matter lesions and brain atrophy are both present early in multiple sclerosis. However, the spatio-temporal relationship between atrophy and lesion processes remains unclear. METHODS: Yearly magnetic resonance images were analyzed in 392 patients with clinically isolated syndrome f...

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Detalles Bibliográficos
Autores principales:	Mattiesing, Rozemarijn M., Gentile, Giordano, Brouwer, Iman, van Schijndel, Ronald A., Uitdehaag, Bernard M.J., Twisk, Jos W.R., Kappos, Ludwig, Freedman, Mark S., Comi, Giancarlo, Jack, Dominic, De Stefano, Nicola, Barkhof, Frederik, Battaglini, Marco, Vrenken, Hugo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668617/ https://www.ncbi.nlm.nih.gov/pubmed/36274376 http://dx.doi.org/10.1016/j.nicl.2022.103220

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