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Inflammatory monocyte gene signature predicts beneficial within group effect of simvastatin in patients with schizophrenia spectrum disorders in a secondary analysis of a randomized controlled trial

Immune dysregulation has been reported in schizophrenia spectrum disorders (SSD). In the past decade, several trials using anti-inflammatory agents for treatment of SSD have been completed, with so far limited success. One such anti-inflammatory agent used is simvastatin. A recent, large-scale, rand...

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Detalles Bibliográficos
Autores principales:	Aichholzer, Mareike, Gangadin, Shiral S., Sommer, Iris E.C., Wijkhuis, Annemarie, de Witte, Lot D., Kahn, René S., Bahn, Sabine, Drexhage, Hemmo A., Schiweck, Carmen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Full Length Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668621/ https://www.ncbi.nlm.nih.gov/pubmed/36405425 http://dx.doi.org/10.1016/j.bbih.2022.100551

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