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cGAMP-adjuvanted multivalent influenza mRNA vaccines induce broadly protective immunity through cutaneous vaccination in mice

Increasing preclinical and clinical results have demonstrated that mRNA vaccines efficiently prevent infectious diseases and are safe in animal models and humans. In this study, we fabricated a multivalent influenza mRNA lipid nanoparticle (LNP) vaccine with mRNAs of hemagglutinins from influenza H1...

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Detalles Bibliográficos
Autores principales: Zhu, Wandi, Wei, Lai, Dong, Chunhong, Wang, Ye, Kim, Joo, Ma, Yao, Gonzalez, Gilbert X., Wang, Bao-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668623/
https://www.ncbi.nlm.nih.gov/pubmed/36420215
http://dx.doi.org/10.1016/j.omtn.2022.10.024

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