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Stabilization of hESCs in two distinct substates along the continuum of pluripotency

A detailed understanding of the developmental substates of human pluripotent stem cells (hPSCs) is needed to optimize their use in cell therapy and for modeling early development. Genetic instability and risk of tumorigenicity of primed hPSCs are well documented, but a systematic isogenic comparison...

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Detalles Bibliográficos
Autores principales:	Dekel, Chen, Morey, Robert, Hanna, Jacob, Laurent, Louise C., Ben-Yosef, Dalit, Amir, Hadar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668692/ https://www.ncbi.nlm.nih.gov/pubmed/36404921 http://dx.doi.org/10.1016/j.isci.2022.105469

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