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Spatial genomics maps the structure, nature and evolution of cancer clones
Genome sequencing of cancers often reveals mosaics of different subclones present in the same tumour(1–3). Although these are believed to arise according to the principles of somatic evolution, the exact spatial growth patterns and underlying mechanisms remain elusive(4,5). Here, to address this nee...
Autores principales: | Lomakin, Artem, Svedlund, Jessica, Strell, Carina, Gataric, Milana, Shmatko, Artem, Rukhovich, Gleb, Park, Jun Sung, Ju, Young Seok, Dentro, Stefan, Kleshchevnikov, Vitalii, Vaskivskyi, Vasyl, Li, Tong, Bayraktar, Omer Ali, Pinder, Sarah, Richardson, Andrea L., Santagata, Sandro, Campbell, Peter J., Russnes, Hege, Gerstung, Moritz, Nilsson, Mats, Yates, Lucy R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668746/ https://www.ncbi.nlm.nih.gov/pubmed/36352222 http://dx.doi.org/10.1038/s41586-022-05425-2 |
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