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Targeting arginase-1 exerts antitumor effects in multiple myeloma and mitigates bortezomib-induced cardiotoxicity

Multiple myeloma (MM) remains an incurable malignancy of plasma cells despite constantly evolving therapeutic approaches including various types of immunotherapy. Increased arginase activity has been associated with potent suppression of T-cell immune responses in different types of cancer. Here, we...

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Detalles Bibliográficos
Autores principales:	Ramji, Kavita, Grzywa, Tomasz M., Sosnowska, Anna, Paterek, Aleksandra, Okninska, Marta, Pilch, Zofia, Barankiewicz, Joanna, Garbicz, Filip, Borg, Katarzyna, Bany-Laszewicz, Urszula, Zerrouqi, Abdesamad, Pyrzynska, Beata, Rodziewicz-Lurzynska, Anna, Papiernik, Diana, Sklepkiewicz, Piotr, Kedzierska, Hanna, Staruch, Adam, Sadowski, Radoslaw, Ciepiela, Olga, Lech-Maranda, Ewa, Juszczynski, Przemyslaw, Mackiewicz, Urszula, Maczewski, Michal, Nowis, Dominika, Golab, Jakub
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668840/ https://www.ncbi.nlm.nih.gov/pubmed/36385153 http://dx.doi.org/10.1038/s41598-022-24137-1

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