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Ascertaining cells’ synaptic connections and RNA expression simultaneously with barcoded rabies virus libraries

Brain function depends on synaptic connections between specific neuron types, yet systematic descriptions of synaptic networks and their molecular properties are not readily available. Here, we introduce SBARRO (Synaptic Barcode Analysis by Retrograde Rabies ReadOut), a method that uses single-cell...

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Detalles Bibliográficos
Autores principales: Saunders, Arpiar, Huang, Kee Wui, Vondrak, Cassandra, Hughes, Christina, Smolyar, Karina, Sen, Harsha, Philson, Adrienne C., Nemesh, James, Wysoker, Alec, Kashin, Seva, Sabatini, Bernardo L., McCarroll, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668842/
https://www.ncbi.nlm.nih.gov/pubmed/36384944
http://dx.doi.org/10.1038/s41467-022-34334-1