Sulfur amino acid supplementation displays therapeutic potential in a C. elegans model of Duchenne muscular dystrophy

Mutations in the dystrophin gene cause Duchenne muscular dystrophy (DMD), a common muscle disease that manifests with muscle weakness, wasting, and degeneration. An emerging theme in DMD pathophysiology is an intramuscular deficit in the gasotransmitter hydrogen sulfide (H(2)S). Here we show that th...

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Detalles Bibliográficos
Autores principales: Ellwood, Rebecca A., Slade, Luke, Lewis, Jonathan, Torregrossa, Roberta, Sudevan, Surabhi, Piasecki, Mathew, Whiteman, Matthew, Etheridge, Timothy, Szewczyk, Nathaniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668843/
https://www.ncbi.nlm.nih.gov/pubmed/36385509
http://dx.doi.org/10.1038/s42003-022-04212-z

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