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Cryo-EM structure of the agonist-bound Hsp90-XAP2-AHR cytosolic complex

The aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor that mediates a broad spectrum of (patho)physiological processes in response to numerous substances including pollutants, natural products and metabolites. However, the scarcity of structural data precludes understanding...

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Detalles Bibliográficos
Autores principales:	Gruszczyk, Jakub, Grandvuillemin, Loïc, Lai-Kee-Him, Josephine, Paloni, Matteo, Savva, Christos G., Germain, Pierre, Grimaldi, Marina, Boulahtouf, Abdelhay, Kwong, Hok-Sau, Bous, Julien, Ancelin, Aurélie, Bechara, Cherine, Barducci, Alessandro, Balaguer, Patrick, Bourguet, William
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668932/ https://www.ncbi.nlm.nih.gov/pubmed/36385050 http://dx.doi.org/10.1038/s41467-022-34773-w

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