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The progressive ratio and fixed ratio 1 schedules of cocaine self-administration in rats convey the same information
Progressive ratio (PR) schedules of drug delivery are used to determine the ‘motivational’ state of an animal and drug ‘reinforcing efficacy’. This widely held interpretation is supported mainly by the observation that the PR breakpoint (BP) is proportional to the unit dose of self-administered drug...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9668967/ https://www.ncbi.nlm.nih.gov/pubmed/36385347 http://dx.doi.org/10.1038/s41598-022-24173-x |