YAP promotes cell-autonomous immune responses to tackle intracellular Staphylococcus aureus in vitro

Transcriptional cofactors YAP/TAZ have recently been found to support autophagy and inflammation, which are part of cell-autonomous immunity and are critical in antibacterial defense. Here, we studied the role of YAP against Staphylococcus aureus using CRISPR/Cas9-mutated HEK293 cells and a primary...

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Detalles Bibliográficos
Autores principales: Caire, Robin, Audoux, Estelle, Thomas, Mireille, Dalix, Elisa, Peyron, Aurélien, Rodriguez, Killian, Pordone, Nicola, Guillemot, Johann, Dickerscheit, Yann, Marotte, Hubert, Vandenesch, François, Laurent, Frédéric, Josse, Jérôme, Verhoeven, Paul O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669043/
https://www.ncbi.nlm.nih.gov/pubmed/36384856
http://dx.doi.org/10.1038/s41467-022-34432-0

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