Determination of dexamethasone dose for cortisol suppression in adult common marmosets (Callithrix jacchus)

We conducted a dose–response study of dexamethasone to investigate an optimal dexamethasone suppression test for common marmosets. Twelve marmosets received 0.1, 0.5, or 1.0 mg/kg dexamethasone. Doses of 0.5 and 1.0 mg/kg both suppressed endogenous cortisol for at least 18 h with greater individual...

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Detalles Bibliográficos
Autores principales: Phillips, Kimberley A., Lopez, Matthew, Salmon, Adam B., Ross, Corinna N., Abbott, David H., Capitanio, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Short Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669144/
https://www.ncbi.nlm.nih.gov/pubmed/35791288
http://dx.doi.org/10.1111/jmp.12602
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author Phillips, Kimberley A.
Lopez, Matthew
Salmon, Adam B.
Ross, Corinna N.
Abbott, David H.
Capitanio, John P.
author_facet Phillips, Kimberley A.
Lopez, Matthew
Salmon, Adam B.
Ross, Corinna N.
Abbott, David H.
Capitanio, John P.
author_sort Phillips, Kimberley A.
collection PubMed
description We conducted a dose–response study of dexamethasone to investigate an optimal dexamethasone suppression test for common marmosets. Twelve marmosets received 0.1, 0.5, or 1.0 mg/kg dexamethasone. Doses of 0.5 and 1.0 mg/kg both suppressed endogenous cortisol for at least 18 h with greater individual variability in the lower 0.5 mg/kg dose.
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spelling pubmed-96691442023-01-04 Determination of dexamethasone dose for cortisol suppression in adult common marmosets (Callithrix jacchus) Phillips, Kimberley A. Lopez, Matthew Salmon, Adam B. Ross, Corinna N. Abbott, David H. Capitanio, John P. J Med Primatol Short Reports We conducted a dose–response study of dexamethasone to investigate an optimal dexamethasone suppression test for common marmosets. Twelve marmosets received 0.1, 0.5, or 1.0 mg/kg dexamethasone. Doses of 0.5 and 1.0 mg/kg both suppressed endogenous cortisol for at least 18 h with greater individual variability in the lower 0.5 mg/kg dose. John Wiley and Sons Inc. 2022-07-05 2022-12 /pmc/articles/PMC9669144/ /pubmed/35791288 http://dx.doi.org/10.1111/jmp.12602 Text en © 2022 The Authors. Journal of Medical Primatology published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Short Reports
Phillips, Kimberley A.
Lopez, Matthew
Salmon, Adam B.
Ross, Corinna N.
Abbott, David H.
Capitanio, John P.
Determination of dexamethasone dose for cortisol suppression in adult common marmosets (Callithrix jacchus)
title Determination of dexamethasone dose for cortisol suppression in adult common marmosets (Callithrix jacchus)
title_full Determination of dexamethasone dose for cortisol suppression in adult common marmosets (Callithrix jacchus)
title_fullStr Determination of dexamethasone dose for cortisol suppression in adult common marmosets (Callithrix jacchus)
title_full_unstemmed Determination of dexamethasone dose for cortisol suppression in adult common marmosets (Callithrix jacchus)
title_short Determination of dexamethasone dose for cortisol suppression in adult common marmosets (Callithrix jacchus)
title_sort determination of dexamethasone dose for cortisol suppression in adult common marmosets (callithrix jacchus)
topic Short Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669144/
https://www.ncbi.nlm.nih.gov/pubmed/35791288
http://dx.doi.org/10.1111/jmp.12602
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