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Scalable manufacturing platform for the production of PEGylated heme albumin
Cell‐free heme, which was previously shown to have adverse effects on the innate immune system, does not induce inflammation when bound to a protein carrier via overexpression of the enzyme heme‐oxygenase 1 (HO‐1). Studies in mouse macrophage cell culture and human endothelial cells have confirmed H...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669187/ https://www.ncbi.nlm.nih.gov/pubmed/36111455 http://dx.doi.org/10.1002/bit.28237 |