Molecular mechanisms of anti-cancer bioactivities of seaweed polysaccharides

Seaweed is a traditional Chinese medicine homologous to food, in which polysaccharides are responsible for anti-cancer by enhancing immunity, inducing cancer cell apoptosis, inhibiting cancer cell invasion and metastasis or directly scavenging oxidative free radicals that induce cancer cell changes....

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Detalles Bibliográficos
Autores principales: Liu, Tingting, Li, Qing, Xu, Xu, Li, Guoxia, Tian, Chengwang, Zhang, Tiejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669349/
https://www.ncbi.nlm.nih.gov/pubmed/36405064
http://dx.doi.org/10.1016/j.chmed.2022.02.003
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author Liu, Tingting
Li, Qing
Xu, Xu
Li, Guoxia
Tian, Chengwang
Zhang, Tiejun
author_facet Liu, Tingting
Li, Qing
Xu, Xu
Li, Guoxia
Tian, Chengwang
Zhang, Tiejun
author_sort Liu, Tingting
collection PubMed
description Seaweed is a traditional Chinese medicine homologous to food, in which polysaccharides are responsible for anti-cancer by enhancing immunity, inducing cancer cell apoptosis, inhibiting cancer cell invasion and metastasis or directly scavenging oxidative free radicals that induce cancer cell changes. Among them, regulating immunity and promoting cancer cell apoptosis are intensively studied due to the important role in preventing cancer. Here we reviewed seaweed in the apoptosis-inducing signaling pathways including PI3K/AKT, ROS and JNK and discussed challenges in studying seaweed.
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spelling pubmed-96693492022-11-18 Molecular mechanisms of anti-cancer bioactivities of seaweed polysaccharides Liu, Tingting Li, Qing Xu, Xu Li, Guoxia Tian, Chengwang Zhang, Tiejun Chin Herb Med Review Seaweed is a traditional Chinese medicine homologous to food, in which polysaccharides are responsible for anti-cancer by enhancing immunity, inducing cancer cell apoptosis, inhibiting cancer cell invasion and metastasis or directly scavenging oxidative free radicals that induce cancer cell changes. Among them, regulating immunity and promoting cancer cell apoptosis are intensively studied due to the important role in preventing cancer. Here we reviewed seaweed in the apoptosis-inducing signaling pathways including PI3K/AKT, ROS and JNK and discussed challenges in studying seaweed. Elsevier 2022-05-13 /pmc/articles/PMC9669349/ /pubmed/36405064 http://dx.doi.org/10.1016/j.chmed.2022.02.003 Text en © 2022 Tianjin Press of Chinese Herbal Medicines. Published by ELSEVIER B.V. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review
Liu, Tingting
Li, Qing
Xu, Xu
Li, Guoxia
Tian, Chengwang
Zhang, Tiejun
Molecular mechanisms of anti-cancer bioactivities of seaweed polysaccharides
title Molecular mechanisms of anti-cancer bioactivities of seaweed polysaccharides
title_full Molecular mechanisms of anti-cancer bioactivities of seaweed polysaccharides
title_fullStr Molecular mechanisms of anti-cancer bioactivities of seaweed polysaccharides
title_full_unstemmed Molecular mechanisms of anti-cancer bioactivities of seaweed polysaccharides
title_short Molecular mechanisms of anti-cancer bioactivities of seaweed polysaccharides
title_sort molecular mechanisms of anti-cancer bioactivities of seaweed polysaccharides
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669349/
https://www.ncbi.nlm.nih.gov/pubmed/36405064
http://dx.doi.org/10.1016/j.chmed.2022.02.003
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