Cargando…

Pharmacological and analytical aspects of alkannin/shikonin and their derivatives: An update from 2008 to 2022

Alkannin/shikonin (A/S) and their derivatives are naturally occurring naphthoquinones majorly found in Boraginaceae family plants. They are integral constituents of traditional Chinese medicine Zicao (roots of Lithospermum erythrorhizon). In last two decades significant increase in pharmacological i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kaur, Kirandeep, Sharma, Rashi, Singh, Atamjit, Attri, Shivani, Arora, Saroj, Kaur, Sarabjit, Bedi, Neena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669360/ https://www.ncbi.nlm.nih.gov/pubmed/36405061 http://dx.doi.org/10.1016/j.chmed.2022.08.001

Ejemplares similares

Bacterial responses to plant antimicrobials: the case of alkannin and shikonin derivatives
por: Rat, Angélique, et al.
Publicado: (2023)

Expanding the Biological Properties of Alkannins and Shikonins: Their Impact on Adipogenesis and Life Expectancy in Nematodes
por: Arampatzis, Athanasios S., et al.
Publicado: (2022)

Dynamics of alkannin/shikonin biosynthesis in response to jasmonate and salicylic acid in Lithospermum officinale
por: Ahmad, Muhammad, et al.
Publicado: (2022)

Novel electrospun poly-hydroxybutyrate scaffolds as carriers for the wound healing agents alkannins and shikonins
por: Arampatzis, Athanasios S, et al.
Publicado: (2021)

Exploring the evolutionary process of alkannin/shikonin O-acyltransferases by a reliable Lithospermum erythrorhizon genome
por: Tang, Chengyi
Publicado: (2021)

Transcriptional dynamics of Chitinophaga sp. strain R-73072-mediated alkannin/shikonin biosynthesis in Lithospermum officinale
por: Ahmad, Muhammad, et al.
Publicado: (2022)

Neuromodulatory effect of 4-(methylthio)butyl isothiocyanate against 3-nitropropionic acid induced oxidative impairments in human dopaminergic SH-SY5Y cells via BDNF/CREB/TrkB pathway
por: Kaur, Prabhjot, et al.
Publicado: (2023)

Frankincense oil-loaded nanoemulsion formulation of paclitaxel and erucin: A synergistic combination for ameliorating drug resistance in breast cancer: In vitro and in vivo study
por: Kaur, Harneetpal, et al.
Publicado: (2022)

Development and optimization of nanoparticles loaded with erucin, a dietary isothiocyanate isolated from Eruca sativa: Antioxidant and antiproliferative activities in ehrlich-ascites carcinoma cell line
por: Singh, Sharabjit, et al.
Publicado: (2023)

Arbuscular mycorrhizal fungi impact the production of alkannin/shikonin and their derivatives in Alkanna tinctoria Tausch. grown in semi-hydroponic and pot cultivation systems
por: Zhao, Yanyan, et al.
Publicado: (2023)

Protective effect of Grewia asiatica leaves extract in animal models of epilepsy and anxiety
por: Kaur, Shabnampreet, et al.
Publicado: (2022)

Review of Shikonin and Derivatives: Isolation, Chemistry, Biosynthesis, Pharmacology and Toxicology
por: Yadav, Snehlata, et al.
Publicado: (2022)

Alkannin Inhibits the Development of Ovarian Cancer by Affecting miR-4461
por: Wang, Yaowen, et al.
Publicado: (2021)

Comparative evaluation of ropivacaine versus dexmedetomidine and ropivacaine in epidural anesthesia in lower limb orthopedic surgeries
por: Kaur, Sarabjit, et al.
Publicado: (2014)

Neuroprotective activity of novel phenanthrene derivative from Grewia tiliaefolia by in vitro and in silico studies
por: Rajput, Ankita, et al.
Publicado: (2023)

Comparison of levobupivacaine and levobupivacaine with fentanyl in infraumbilical surgeries under spinal anaesthesia
por: Attri, Joginder Pal, et al.
Publicado: (2015)

Comparative Evaluation of Ketamine - Propofol, Fentanyl - Propofol and Butorphanol-Propofol on Haemodynamics and Laryngeal Mask Airway Insertion Conditions
por: Gupta, Asha, et al.
Publicado: (2011)

Alkannin, HSP70 Inducer, Protects against UVB-Induced Apoptosis in Human Keratinocytes
por: Yoshihisa, Yoko, et al.
Publicado: (2012)

Antioxidant and chemoprotective potential of Streptomyces levis strain isolated from human gut
por: Verma, Jaya, et al.
Publicado: (2023)

Alkannin-Induced Oxidative DNA Damage Synergizes With PARP Inhibition to Cause Cancer-Specific Cytotoxicity
por: Chang, Mingxin, et al.
Publicado: (2020)

Antiproliferative Effects of Roylea cinerea (D. Don) Baillon Leaves in Immortalized L6 Rat Skeletal Muscle Cell Line: Role of Reactive Oxygen Species Mediated Pathway
por: Bhatia, Astha, et al.
Publicado: (2020)

Synthesis of Novel Shikonin Derivatives and Pharmacological Effects of Cyclopropylacetylshikonin on Melanoma Cells
por: Durchschein, Christin, et al.
Publicado: (2018)

Modified drug regimen for ophthalmic anesthesia during COVID-19 pandemic: Revisiting pharmacological concepts
por: Gurnani, Bharat, et al.
Publicado: (2021)

Rhino-orbital-cerebral mucormycosis in COVID-19 patients – Taming the black evil with pharmacological weapons
por: Kaur, Kirandeep, et al.
Publicado: (2021)

Modulation of atrazine-induced chromosomal aberrations and cyclin-dependent kinases by aqueous extract of Roylea cinerea (D.Don) Baillon leaves in Allium cepa
por: Rashid, Farhana, et al.
Publicado: (2022)

Protective role of Phyllanthusfraternus in alloxan-induced diabetes in rats
por: Singh, Hasandeep, et al.
Publicado: (2020)

Smoking cessation
por: Kaur, Kirandeep, et al.
Publicado: (2012)

Alkannin reverses lipopolysaccharides-induced inflammatory responses by suppressing mitogen-activated protein kinase and nuclear factor kappa-B signalling
por: Yang, Jingya, et al.
Publicado: (2023)

Phytoconstituents from ten natural herbs as potent inhibitors of main protease enzyme of SARS-COV-2: In silico study
por: Kumar, Nitish, et al.
Publicado: (2021)

Neurobiology of the trace amines: analytical, physiological, pharmacological, behavioral, and clinical aspects
por: Boulton, A, et al.
Publicado: (1984)

A review on pharmacological and analytical aspects of diosgenin: a concise report
por: Patel, Kanika, et al.
Publicado: (2012)

Effect of 3, hydroxy-lup- 20(29)-en-28-oic acid on 7,12-Dimethylbenz(a) anthracene impaired cellular homeostasis in extrahepatic organs of Sprague Dawley rats
por: Kaur, Pardeep, et al.
Publicado: (2017)

Delineation of attenuation of oxidative stress and mutagenic stress by Murraya exotica L. leaves
por: Kaur, Davinder, et al.
Publicado: (2016)

Synthesis and Pharmacological In Vitro Investigations of Novel Shikonin Derivatives with a Special Focus on Cyclopropane Bearing Derivatives
por: Kretschmer, Nadine, et al.
Publicado: (2021)

Design, Synthesis, Antimicrobial Evaluation, and Molecular Modeling Studies of Novel Indolinedione–Coumarin Molecular Hybrids
por: Bhagat, Kavita, et al.
Publicado: (2019)

Medicinal importance, pharmacological activities, and analytical aspects of hispidulin: A concise report
por: Patel, Kanika, et al.
Publicado: (2016)

Evaluation of radical scavenging properties of shikonin
por: Yoshida, Lucia S., et al.
Publicado: (2014)

Promising Nanomedicines of Shikonin for Cancer Therapy
por: Yan, Chunmei, et al.
Publicado: (2023)

Integrative analysis of the shikonin metabolic network identifies new gene connections and reveals evolutionary insight into shikonin biosynthesis
por: Suttiyut, Thiti, et al.
Publicado: (2022)

Gut microbiota and Autism Spectrum Disorder: From pathogenesis to potential therapeutic perspectives
por: Mehra, Anshula, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_2tbooctm20du9dlui91uqt5rpm