Cognitive dysfunctions in high myopia: An overview of potential neural morpho-functional mechanisms

Dementia and cognitive impairment (CIM) carry high levels of mortality. Visual impairment (VI) is linked with CIM risk. High myopia (HM) is a chronic disease frequently leading to irreversible blindness. Current opinion has shifted from retinal injury as the cause of HM to the condition being consid...

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Autores principales: Li, Kaixiu, Wang, Qun, Wang, Liqiang, Huang, Yifei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669364/
https://www.ncbi.nlm.nih.gov/pubmed/36408499
http://dx.doi.org/10.3389/fneur.2022.1022944
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author Li, Kaixiu
Wang, Qun
Wang, Liqiang
Huang, Yifei
author_facet Li, Kaixiu
Wang, Qun
Wang, Liqiang
Huang, Yifei
author_sort Li, Kaixiu
collection PubMed
description Dementia and cognitive impairment (CIM) carry high levels of mortality. Visual impairment (VI) is linked with CIM risk. High myopia (HM) is a chronic disease frequently leading to irreversible blindness. Current opinion has shifted from retinal injury as the cause of HM to the condition being considered an eye-brain disease. However, the pathogenesis of this disease and the manner in which neural structures are damaged are poorly understood. This review comprehensively discusses the relationship between HM, the central nervous system, and CIM, together with the novel concept of three visual pathways, and possible research perspectives.
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spelling pubmed-96693642022-11-18 Cognitive dysfunctions in high myopia: An overview of potential neural morpho-functional mechanisms Li, Kaixiu Wang, Qun Wang, Liqiang Huang, Yifei Front Neurol Neurology Dementia and cognitive impairment (CIM) carry high levels of mortality. Visual impairment (VI) is linked with CIM risk. High myopia (HM) is a chronic disease frequently leading to irreversible blindness. Current opinion has shifted from retinal injury as the cause of HM to the condition being considered an eye-brain disease. However, the pathogenesis of this disease and the manner in which neural structures are damaged are poorly understood. This review comprehensively discusses the relationship between HM, the central nervous system, and CIM, together with the novel concept of three visual pathways, and possible research perspectives. Frontiers Media S.A. 2022-11-03 /pmc/articles/PMC9669364/ /pubmed/36408499 http://dx.doi.org/10.3389/fneur.2022.1022944 Text en Copyright © 2022 Li, Wang, Wang and Huang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Li, Kaixiu
Wang, Qun
Wang, Liqiang
Huang, Yifei
Cognitive dysfunctions in high myopia: An overview of potential neural morpho-functional mechanisms
title Cognitive dysfunctions in high myopia: An overview of potential neural morpho-functional mechanisms
title_full Cognitive dysfunctions in high myopia: An overview of potential neural morpho-functional mechanisms
title_fullStr Cognitive dysfunctions in high myopia: An overview of potential neural morpho-functional mechanisms
title_full_unstemmed Cognitive dysfunctions in high myopia: An overview of potential neural morpho-functional mechanisms
title_short Cognitive dysfunctions in high myopia: An overview of potential neural morpho-functional mechanisms
title_sort cognitive dysfunctions in high myopia: an overview of potential neural morpho-functional mechanisms
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669364/
https://www.ncbi.nlm.nih.gov/pubmed/36408499
http://dx.doi.org/10.3389/fneur.2022.1022944
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