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Epidemiological and Clinical Characteristics of Patients with Dengue Fever in a Recent Outbreak in Oman: A Single Center Retrospective-cohort Study
OBJECTIVES: Dengue fever (DF) is the most common arthropod-borne viral illness with significant public health implications that can cause severe clinical symptoms and possibly death. We sought to determine the epidemiological and clinical characteristics of patients presented with DF to the Royal Ho...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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OMJ
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669402/ https://www.ncbi.nlm.nih.gov/pubmed/36458248 http://dx.doi.org/10.5001/omj.2023.57 |
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author | Al Awaidy, Salah T. Khamis, Faryal Al-Zakwani, Ibrahim Al Kindi, Shadha Al Busafi, Suad Al Sulaimi, Khalsa Al Sidiari, Hilal |
author_facet | Al Awaidy, Salah T. Khamis, Faryal Al-Zakwani, Ibrahim Al Kindi, Shadha Al Busafi, Suad Al Sulaimi, Khalsa Al Sidiari, Hilal |
author_sort | Al Awaidy, Salah T. |
collection | PubMed |
description | OBJECTIVES: Dengue fever (DF) is the most common arthropod-borne viral illness with significant public health implications that can cause severe clinical symptoms and possibly death. We sought to determine the epidemiological and clinical characteristics of patients presented with DF to the Royal Hospital in a recent outbreak in Oman. METHODS: We conducted a retrospective cohort study between 1 January and 18 April 2022, at the Royal Hospital, Oman, including all patients who presented with febrile illness and laboratory-confirmed DF. Descriptive statistics were used to summarize the results. RESULTS: The cohort included 58 patients with laboratory-confirmed DF, of whom 39 (67.2%) required admission. The overall mean age was 41.0±20.0 years. Over half (55.2%) were females and the majority (86.2%) were Omani citizens. Eighty-one percent of the patients were residents of Bawshar in Muscat governorate. Dengue virus 2 was the isolated serotype. Fever (98.3%), muscular aches and pains (55.2%), and headache (53.4%) were the most common symptoms on presentation. All patients except two had no travel history. The most common comorbidities were hypertension (29.3%) and diabetes mellitus (17.2%). Upon admission, the most prominent hematological and biochemical abnormalities were severe thrombocytopenia (31.0%) with platelet counts of < 50 000/mm(3) and hepatic impairment (15.5%). Antibiotics were prescribed to 27.6% of the patients. All patients improved clinically, and no deaths were reported during the study period. CONCLUSIONS: Fever and thrombocytopenia were the commonest presentations of DF. Identification of factors linked to increased risk of hospitalization in patients with DF can assist in recognizing individuals who need close monitoring and intensive support. |
format | Online Article Text |
id | pubmed-9669402 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | OMJ |
record_format | MEDLINE/PubMed |
spelling | pubmed-96694022022-11-30 Epidemiological and Clinical Characteristics of Patients with Dengue Fever in a Recent Outbreak in Oman: A Single Center Retrospective-cohort Study Al Awaidy, Salah T. Khamis, Faryal Al-Zakwani, Ibrahim Al Kindi, Shadha Al Busafi, Suad Al Sulaimi, Khalsa Al Sidiari, Hilal Oman Med J Original Articles OBJECTIVES: Dengue fever (DF) is the most common arthropod-borne viral illness with significant public health implications that can cause severe clinical symptoms and possibly death. We sought to determine the epidemiological and clinical characteristics of patients presented with DF to the Royal Hospital in a recent outbreak in Oman. METHODS: We conducted a retrospective cohort study between 1 January and 18 April 2022, at the Royal Hospital, Oman, including all patients who presented with febrile illness and laboratory-confirmed DF. Descriptive statistics were used to summarize the results. RESULTS: The cohort included 58 patients with laboratory-confirmed DF, of whom 39 (67.2%) required admission. The overall mean age was 41.0±20.0 years. Over half (55.2%) were females and the majority (86.2%) were Omani citizens. Eighty-one percent of the patients were residents of Bawshar in Muscat governorate. Dengue virus 2 was the isolated serotype. Fever (98.3%), muscular aches and pains (55.2%), and headache (53.4%) were the most common symptoms on presentation. All patients except two had no travel history. The most common comorbidities were hypertension (29.3%) and diabetes mellitus (17.2%). Upon admission, the most prominent hematological and biochemical abnormalities were severe thrombocytopenia (31.0%) with platelet counts of < 50 000/mm(3) and hepatic impairment (15.5%). Antibiotics were prescribed to 27.6% of the patients. All patients improved clinically, and no deaths were reported during the study period. CONCLUSIONS: Fever and thrombocytopenia were the commonest presentations of DF. Identification of factors linked to increased risk of hospitalization in patients with DF can assist in recognizing individuals who need close monitoring and intensive support. OMJ 2022-11-30 /pmc/articles/PMC9669402/ /pubmed/36458248 http://dx.doi.org/10.5001/omj.2023.57 Text en The OMJ is Published Bimonthly and Copyrighted 2022 by the OMSB. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial (CC BY-NC) 4.0 License. http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) |
spellingShingle | Original Articles Al Awaidy, Salah T. Khamis, Faryal Al-Zakwani, Ibrahim Al Kindi, Shadha Al Busafi, Suad Al Sulaimi, Khalsa Al Sidiari, Hilal Epidemiological and Clinical Characteristics of Patients with Dengue Fever in a Recent Outbreak in Oman: A Single Center Retrospective-cohort Study |
title | Epidemiological and Clinical Characteristics of Patients with Dengue Fever in a Recent Outbreak in Oman: A Single Center Retrospective-cohort Study |
title_full | Epidemiological and Clinical Characteristics of Patients with Dengue Fever in a Recent Outbreak in Oman: A Single Center Retrospective-cohort Study |
title_fullStr | Epidemiological and Clinical Characteristics of Patients with Dengue Fever in a Recent Outbreak in Oman: A Single Center Retrospective-cohort Study |
title_full_unstemmed | Epidemiological and Clinical Characteristics of Patients with Dengue Fever in a Recent Outbreak in Oman: A Single Center Retrospective-cohort Study |
title_short | Epidemiological and Clinical Characteristics of Patients with Dengue Fever in a Recent Outbreak in Oman: A Single Center Retrospective-cohort Study |
title_sort | epidemiological and clinical characteristics of patients with dengue fever in a recent outbreak in oman: a single center retrospective-cohort study |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669402/ https://www.ncbi.nlm.nih.gov/pubmed/36458248 http://dx.doi.org/10.5001/omj.2023.57 |
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