Loss of mitochondrial enzyme GPT2 causes early neurodegeneration in locus coeruleus

Locus coeruleus (LC) is among the first brain areas to degenerate in Alzheimer’s disease and Parkinson’s disease; however, the underlying causes for the vulnerability of LC neurons are not well defined. Here we report a novel mechanism of degeneration of LC neurons caused by loss of the mitochondria...

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Detalles Bibliográficos
Autores principales: Baytas, Ozan, Kauer, Julie A., Morrow, Eric M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669404/
https://www.ncbi.nlm.nih.gov/pubmed/35908744
http://dx.doi.org/10.1016/j.nbd.2022.105831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669404/
https://www.ncbi.nlm.nih.gov/pubmed/35908744
http://dx.doi.org/10.1016/j.nbd.2022.105831

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