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Loss of mitochondrial enzyme GPT2 causes early neurodegeneration in locus coeruleus
Locus coeruleus (LC) is among the first brain areas to degenerate in Alzheimer’s disease and Parkinson’s disease; however, the underlying causes for the vulnerability of LC neurons are not well defined. Here we report a novel mechanism of degeneration of LC neurons caused by loss of the mitochondria...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669404/ https://www.ncbi.nlm.nih.gov/pubmed/35908744 http://dx.doi.org/10.1016/j.nbd.2022.105831 |