Dietary choline, via gut microbe- generated trimethylamine-N- oxide, aggravates chronic kidney disease-induced cardiac dysfunction by inhibiting hypoxia-induced factor 1α

Chronic kidney disease (CKD) is a global public health problem that shortens lifespan primarily by increasing the risk of cardiovascular diseases. Trimethylamine-N-oxide (TMAO), a gut microbiota-derived toxin produced by metabolizing high-choline or carnitine foods, is associated with cardiovascular...

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Detalles Bibliográficos
Autores principales: Xie, Feifei, Zhen, Xin, Liu, Zhuoliang, Chen, Xiaomei, Liu, Zhuanhua, Zhou, Miaomiao, Zhou, Zhanmei, Hu, Zheng, Zhu, Fengxin, Huang, Qiaobing, Zhang, Lei, Nie, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669413/
https://www.ncbi.nlm.nih.gov/pubmed/36407000
http://dx.doi.org/10.3389/fphys.2022.996166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669413/
https://www.ncbi.nlm.nih.gov/pubmed/36407000
http://dx.doi.org/10.3389/fphys.2022.996166

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