Case report: A prosthetic valve endocarditis caused by Legionella bozemanae in an immunocompetent patient

Extrapulmonary infections with Legionella species are rare, but important to acknowledge. We report a case of infective endocarditis (IE) with Legionella bozemanae in a 66-year-old immunocompetent man with an aortic homograft. The diagnosis was made by direct 16S rRNA gene amplification from valve m...

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Autores principales: Fraz, Mai Sasaki Aanensen, Dahle, Gry, Skaug, Kirsten Margrete, Jarraud, Sophie, Frye, Stephan, Bjørnholt, Jørgen Vildershøj, Nordøy, Ingvild
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669447/
https://www.ncbi.nlm.nih.gov/pubmed/36405607
http://dx.doi.org/10.3389/fmed.2022.1055465
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author Fraz, Mai Sasaki Aanensen
Dahle, Gry
Skaug, Kirsten Margrete
Jarraud, Sophie
Frye, Stephan
Bjørnholt, Jørgen Vildershøj
Nordøy, Ingvild
author_facet Fraz, Mai Sasaki Aanensen
Dahle, Gry
Skaug, Kirsten Margrete
Jarraud, Sophie
Frye, Stephan
Bjørnholt, Jørgen Vildershøj
Nordøy, Ingvild
author_sort Fraz, Mai Sasaki Aanensen
collection PubMed
description Extrapulmonary infections with Legionella species are rare, but important to acknowledge. We report a case of infective endocarditis (IE) with Legionella bozemanae in a 66-year-old immunocompetent man with an aortic homograft. The diagnosis was made by direct 16S rRNA gene amplification from valve material, confirmed by a targeted Legionella-PCR in serum and the detection of L. bozemanae specific antibodies. To our knowledge, this is the first confirmed case of IE with L. bozemanae as causative pathogen. The infected aortic prosthesis was replaced by a homograft, and the patient was successfully treated with levofloxacin and azithromycin for 6 weeks.
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spelling pubmed-96694472022-11-18 Case report: A prosthetic valve endocarditis caused by Legionella bozemanae in an immunocompetent patient Fraz, Mai Sasaki Aanensen Dahle, Gry Skaug, Kirsten Margrete Jarraud, Sophie Frye, Stephan Bjørnholt, Jørgen Vildershøj Nordøy, Ingvild Front Med (Lausanne) Medicine Extrapulmonary infections with Legionella species are rare, but important to acknowledge. We report a case of infective endocarditis (IE) with Legionella bozemanae in a 66-year-old immunocompetent man with an aortic homograft. The diagnosis was made by direct 16S rRNA gene amplification from valve material, confirmed by a targeted Legionella-PCR in serum and the detection of L. bozemanae specific antibodies. To our knowledge, this is the first confirmed case of IE with L. bozemanae as causative pathogen. The infected aortic prosthesis was replaced by a homograft, and the patient was successfully treated with levofloxacin and azithromycin for 6 weeks. Frontiers Media S.A. 2022-11-03 /pmc/articles/PMC9669447/ /pubmed/36405607 http://dx.doi.org/10.3389/fmed.2022.1055465 Text en Copyright © 2022 Fraz, Dahle, Skaug, Jarraud, Frye, Bjørnholt and Nordøy. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Fraz, Mai Sasaki Aanensen
Dahle, Gry
Skaug, Kirsten Margrete
Jarraud, Sophie
Frye, Stephan
Bjørnholt, Jørgen Vildershøj
Nordøy, Ingvild
Case report: A prosthetic valve endocarditis caused by Legionella bozemanae in an immunocompetent patient
title Case report: A prosthetic valve endocarditis caused by Legionella bozemanae in an immunocompetent patient
title_full Case report: A prosthetic valve endocarditis caused by Legionella bozemanae in an immunocompetent patient
title_fullStr Case report: A prosthetic valve endocarditis caused by Legionella bozemanae in an immunocompetent patient
title_full_unstemmed Case report: A prosthetic valve endocarditis caused by Legionella bozemanae in an immunocompetent patient
title_short Case report: A prosthetic valve endocarditis caused by Legionella bozemanae in an immunocompetent patient
title_sort case report: a prosthetic valve endocarditis caused by legionella bozemanae in an immunocompetent patient
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669447/
https://www.ncbi.nlm.nih.gov/pubmed/36405607
http://dx.doi.org/10.3389/fmed.2022.1055465
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