Case report of clindamycin graded challenge in an AIDS patient allergic to clindamycin

The aim of this study was to report the success of a clindamycin graded challenge. The patient was a 39-year-old human immunodeficiency virus-infected male with toxoplasmic encephalitis (TE) with a history of trimethoprim/sulfamethoxazole (TMP/SMX) and clindamycin allergy. He developed a reaction du...

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Autores principales: Raknoo, Thitinun, Sae-lim, Orawan, Pattharachayakul, Sutthiporn, Kanchanasuwan, Siripen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asia Pacific Association of Allergy, Asthma and Clinical Immunology 2022
Materias:
Educational & Teaching Material
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669470/
https://www.ncbi.nlm.nih.gov/pubmed/36452008
http://dx.doi.org/10.5415/apallergy.2022.12.e36
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author Raknoo, Thitinun
Sae-lim, Orawan
Pattharachayakul, Sutthiporn
Kanchanasuwan, Siripen
author_facet Raknoo, Thitinun
Sae-lim, Orawan
Pattharachayakul, Sutthiporn
Kanchanasuwan, Siripen
author_sort Raknoo, Thitinun
collection PubMed
description The aim of this study was to report the success of a clindamycin graded challenge. The patient was a 39-year-old human immunodeficiency virus-infected male with toxoplasmic encephalitis (TE) with a history of trimethoprim/sulfamethoxazole (TMP/SMX) and clindamycin allergy. He developed a reaction during TMP/SMX desensitization. Following the reaction, a graded challenge with clindamycin was performed in this study, and he became tolerant to clindamycin. No adverse drug reactions developed during the graded challenge. He successfully continued suppressive therapy with no further reactions or recurrences.
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spelling pubmed-96694702022-11-29 Case report of clindamycin graded challenge in an AIDS patient allergic to clindamycin Raknoo, Thitinun Sae-lim, Orawan Pattharachayakul, Sutthiporn Kanchanasuwan, Siripen Asia Pac Allergy Educational & Teaching Material The aim of this study was to report the success of a clindamycin graded challenge. The patient was a 39-year-old human immunodeficiency virus-infected male with toxoplasmic encephalitis (TE) with a history of trimethoprim/sulfamethoxazole (TMP/SMX) and clindamycin allergy. He developed a reaction during TMP/SMX desensitization. Following the reaction, a graded challenge with clindamycin was performed in this study, and he became tolerant to clindamycin. No adverse drug reactions developed during the graded challenge. He successfully continued suppressive therapy with no further reactions or recurrences. Asia Pacific Association of Allergy, Asthma and Clinical Immunology 2022-10-17 /pmc/articles/PMC9669470/ /pubmed/36452008 http://dx.doi.org/10.5415/apallergy.2022.12.e36 Text en Copyright © 2022. Asia Pacific Association of Allergy, Asthma and Clinical Immunology. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Educational & Teaching Material
Raknoo, Thitinun
Sae-lim, Orawan
Pattharachayakul, Sutthiporn
Kanchanasuwan, Siripen
Case report of clindamycin graded challenge in an AIDS patient allergic to clindamycin
title Case report of clindamycin graded challenge in an AIDS patient allergic to clindamycin
title_full Case report of clindamycin graded challenge in an AIDS patient allergic to clindamycin
title_fullStr Case report of clindamycin graded challenge in an AIDS patient allergic to clindamycin
title_full_unstemmed Case report of clindamycin graded challenge in an AIDS patient allergic to clindamycin
title_short Case report of clindamycin graded challenge in an AIDS patient allergic to clindamycin
title_sort case report of clindamycin graded challenge in an aids patient allergic to clindamycin
topic Educational & Teaching Material
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669470/
https://www.ncbi.nlm.nih.gov/pubmed/36452008
http://dx.doi.org/10.5415/apallergy.2022.12.e36
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