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Studying the interaction between PEX5 and its full-length cargo proteins in living cells by a novel Försteŕs resonance energy transfer-based competition assay

The import of the majority of soluble peroxisomal proteins is initiated by the interaction between type-1 peroxisomal targeting signals (PTS1) and their receptor PEX5. PTS1 motifs reside at the extreme C-terminus of proteins and consist of a characteristic tripeptide and a modulatory upstream region...

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Detalles Bibliográficos
Autores principales: Hochreiter, Bernhard, Malagon-Vina, Hugo, Schmid, Johannes A., Berger, Johannes, Kunze, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669585/
https://www.ncbi.nlm.nih.gov/pubmed/36407094
http://dx.doi.org/10.3389/fcell.2022.1026388