Cargando…

Dietary ketosis improves circadian dysfunction as well as motor symptoms in the BACHD mouse model of Huntington’s disease

Disturbances in sleep/wake cycles are common among patients with neurodegenerative diseases including Huntington’s disease (HD) and represent an appealing target for chrono-nutrition-based interventions. In the present work, we sought to determine whether a low-carbohydrate, high-fat diet would amel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Whittaker, Daniel S., Tamai, T. Katherine, Bains, Raj S., Villanueva, Sophia Anne Marie, Luk, Shu Hon Christopher, Dell’Angelica, Derek, Block, Gene D., Ghiani, Cristina A., Colwell, Christopher S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Nutrition
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669764/ https://www.ncbi.nlm.nih.gov/pubmed/36407529 http://dx.doi.org/10.3389/fnut.2022.1034743

Ejemplares similares

Targeted Genetic Reduction of Mutant Huntingtin Lessens Cardiac Pathology in the BACHD Mouse Model of Huntington's Disease
por: Park, Saemi, et al.
Publicado: (2021)

Sex Differences in Circadian Dysfunction in the BACHD Mouse Model of Huntington’s Disease
por: Kuljis, Dika A., et al.
Publicado: (2016)

Sex Differences in Sleep Phenotypes in the BACHD Mouse Model of Huntington’s Disease
por: Chiem, Emily, et al.
Publicado: (2023)

Cardiac Dysfunction in the BACHD Mouse Model of Huntington’s Disease
por: Schroeder, Analyne M., et al.
Publicado: (2016)

Baroreceptor reflex dysfunction in the BACHD mouse model of Huntington’s disease.
por: Schroeder, Analyne M., et al.
Publicado: (2011)

Blue light therapy improves circadian dysfunction as well as motor symptoms in two mouse models of Huntington's disease
por: Wang, Huei-Bin, et al.
Publicado: (2017)

Environment-dependent striatal gene expression in the BACHD rat model for Huntington disease
por: Novati, Arianna, et al.
Publicado: (2018)

BACHD Mice Recapitulate the Striatal Parvalbuminergic Interneuron Loss Found in Huntington’s Disease
por: Rallapalle, Vyshnavi, et al.
Publicado: (2021)

Dysbindin-containing complexes and their proposed functions in brain: from zero to (too) many in a decade
por: Ghiani, Cristina A, et al.
Publicado: (2011)

Reversal Learning and Associative Memory Impairments in a BACHD Rat Model for Huntington Disease
por: Abada, Yah-se K., et al.
Publicado: (2013)

Effects of mutant huntingtin inactivation on Huntington disease‐related behaviours in the BACHD mouse model
por: Cheong, Rachel Y., et al.
Publicado: (2021)

Do Disruptions in the Circadian Timing System Contribute to Autonomic Dysfunction in Huntington’s Disease?
por: Park, Saemi, et al.
Publicado: (2019)

Reduced Motivation in the BACHD Rat Model of Huntington Disease Is Dependent on the Choice of Food Deprivation Strategy
por: Jansson, Erik Karl Håkan, et al.
Publicado: (2014)

The Alteration of Emotion Regulation Precedes the Deficits in Interval Timing in the BACHD Rat Model for Huntington Disease
por: Garces, Daniel, et al.
Publicado: (2018)

The Circadian Clock Gene Period1 Connects the Molecular Clock to Neural Activity in the Suprachiasmatic Nucleus
por: Kudo, Takashi, et al.
Publicado: (2015)

Ketosis and migraine: a systematic review of the literature and meta-analysis
por: Neri, Lenycia de Cassya Lopes, et al.
Publicado: (2023)

Time-Restricted Feeding Improves Circadian Dysfunction as well as Motor Symptoms in the Q175 Mouse Model of Huntington’s Disease
por: Wang, Huei-Bin, et al.
Publicado: (2018)

The BACHD Rat Model of Huntington Disease Shows Specific Deficits in a Test Battery of Motor Function
por: Manfré, Giuseppe, et al.
Publicado: (2017)

Differential Cellular Balance of Olfactory and Vomeronasal Epithelia in a Transgenic BACHD Rat Model of Huntington’s Disease
por: Krysewski, Lina-Marielle, et al.
Publicado: (2022)

Sleep/Wake Disruption in a Mouse Model of BLOC-1 Deficiency
por: Lee, Frank Y., et al.
Publicado: (2018)

Consequences of Exposure to Light at Night on the Pancreatic Islet Circadian Clock and Function in Rats
por: Qian, Jingyi, et al.
Publicado: (2013)

Metabolic and behavioral effects of mutant huntingtin deletion in Sim1 neurons in the BACHD mouse model of Huntington’s disease
por: Soylu-Kucharz, Rana, et al.
Publicado: (2016)

Structural and molecular myelination deficits occur prior to neuronal loss in the YAC128 and BACHD models of Huntington disease
por: Teo, Roy Tang Yi, et al.
Publicado: (2016)

Structural and functional features of medium spiny neurons in the BACHDΔN17 mouse model of Huntington’s Disease
por: Goodliffe, Joseph, et al.
Publicado: (2020)

Further investigation of phenotypes and confounding factors of progressive ratio performance and feeding behavior in the BACHD rat model of Huntington disease
por: Clemensson, Erik Karl Håkan, et al.
Publicado: (2017)

High-Throughput Sequencing of BACHD Mice Reveals Upregulation of Neuroprotective miRNAs at the Pre-Symptomatic Stage of Huntington’s Disease
por: Olmo, Isabella G., et al.
Publicado: (2021)

The use of nutritional supplements to induce ketosis and reduce symptoms associated with keto-induction: a narrative review
por: Harvey, Cliff J. d C., et al.
Publicado: (2018)

Long wavelength light reduces the negative consequences of dim light at night
por: Wang, Huei-Bin, et al.
Publicado: (2023)

Effects of Deletion of Mutant Huntingtin in Steroidogenic Factor 1 Neurons on the Psychiatric and Metabolic Phenotype in the BACHD Mouse Model of Huntington Disease
por: Baldo, Barbara, et al.
Publicado: (2014)

Assessment of Motor Function, Sensory Motor Gating and Recognition Memory in a Novel BACHD Transgenic Rat Model for Huntington Disease
por: Abada, Yah-se K., et al.
Publicado: (2013)

Correction: Further investigation of phenotypes and confounding factors of progressive ratio performance and feeding behavior in the BACHD rat model of Huntington disease
por: Clemensson, Erik Karl Håkan, et al.
Publicado: (2019)

Nutritional Ketosis Increases NAD(+)/NADH Ratio in Healthy Human Brain: An in Vivo Study by (31)P-MRS
por: Xin, Lijing, et al.
Publicado: (2018)

Neurocardiovascular deficits in the Q175 mouse model of Huntington's disease
por: Cutler, Tamara S., et al.
Publicado: (2017)

The BACHD Rat Model of Huntington Disease Shows Signs of Fronto-Striatal Dysfunction in Two Operant Conditioning Tests of Short-Term Memory
por: Clemensson, Erik Karl Håkan, et al.
Publicado: (2017)

Ketosis After Intake of Coconut Oil and Caprylic Acid—With and Without Glucose: A Cross-Over Study in Healthy Older Adults
por: Norgren, Jakob, et al.
Publicado: (2020)

Sexual behavior and testis morphology in the BACHD rat model
por: Novati, Arianna, et al.
Publicado: (2018)

Age-Related Changes in the Circadian System Unmasked by Constant Conditions1,2,3
por: Nakamura, Takahiro J., et al.
Publicado: (2015)

Melatonin treatment of repetitive behavioral deficits in the Cntnap2 mouse model of autism spectrum disorder
por: Wang, Huei Bin, et al.
Publicado: (2020)

Chronic methamphetamine uncovers a circadian rhythm in multiple-unit neural activity in the dorsal striatum which is independent of the suprachiasmatic nucleus
por: Miyazaki, Shota, et al.
Publicado: (2021)

A small molecule p75(NTR) ligand normalizes signalling and reduces Huntington’s disease phenotypes in R6/2 and BACHD mice
por: Simmons, Danielle A., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_3gct6o4aplpgeguvqqdlmd41oe