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Minimal change disease caused by polycythemia vera: A case report
BACKGROUND: Polycythemia vera (PV), often attributed to the JAK2 V617F mutation, is characterized by enhanced red blood cell counts in the peripheral blood. PV-associated renal disease is clinically rare; to date, there have been reports of other chronic kidney diseases related to PV, but no reports...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Baishideng Publishing Group Inc
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669836/ https://www.ncbi.nlm.nih.gov/pubmed/36405274 http://dx.doi.org/10.12998/wjcc.v10.i32.11993 |
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author | Xu, Li Lu, Li-Li Gao, Jian-Dong |
author_facet | Xu, Li Lu, Li-Li Gao, Jian-Dong |
author_sort | Xu, Li |
collection | PubMed |
description | BACKGROUND: Polycythemia vera (PV), often attributed to the JAK2 V617F mutation, is characterized by enhanced red blood cell counts in the peripheral blood. PV-associated renal disease is clinically rare; to date, there have been reports of other chronic kidney diseases related to PV, but no reports on PV-associated minimal change disease. CASE SUMMARY: A 37-year-old man presented with proteinuria and high red blood cell count on January 4, 2021. The patient underwent bone marrow and renal biopsies, then was subsequently diagnosed with PV and minimal change in disease. Hydroxyurea was administered and proteinuria remission was achieved. The patient’s last visit was on April 14, 2022. CONCLUSION: We inferred that there may be a causal relationship between PV and minimal change disease. |
format | Online Article Text |
id | pubmed-9669836 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-96698362022-11-18 Minimal change disease caused by polycythemia vera: A case report Xu, Li Lu, Li-Li Gao, Jian-Dong World J Clin Cases Case Report BACKGROUND: Polycythemia vera (PV), often attributed to the JAK2 V617F mutation, is characterized by enhanced red blood cell counts in the peripheral blood. PV-associated renal disease is clinically rare; to date, there have been reports of other chronic kidney diseases related to PV, but no reports on PV-associated minimal change disease. CASE SUMMARY: A 37-year-old man presented with proteinuria and high red blood cell count on January 4, 2021. The patient underwent bone marrow and renal biopsies, then was subsequently diagnosed with PV and minimal change in disease. Hydroxyurea was administered and proteinuria remission was achieved. The patient’s last visit was on April 14, 2022. CONCLUSION: We inferred that there may be a causal relationship between PV and minimal change disease. Baishideng Publishing Group Inc 2022-11-16 2022-11-16 /pmc/articles/PMC9669836/ /pubmed/36405274 http://dx.doi.org/10.12998/wjcc.v10.i32.11993 Text en ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
spellingShingle | Case Report Xu, Li Lu, Li-Li Gao, Jian-Dong Minimal change disease caused by polycythemia vera: A case report |
title | Minimal change disease caused by polycythemia vera: A case report |
title_full | Minimal change disease caused by polycythemia vera: A case report |
title_fullStr | Minimal change disease caused by polycythemia vera: A case report |
title_full_unstemmed | Minimal change disease caused by polycythemia vera: A case report |
title_short | Minimal change disease caused by polycythemia vera: A case report |
title_sort | minimal change disease caused by polycythemia vera: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669836/ https://www.ncbi.nlm.nih.gov/pubmed/36405274 http://dx.doi.org/10.12998/wjcc.v10.i32.11993 |
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