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Integrated analysis of dermal blister fluid proteomics and genome-wide skin gene expression in systemic sclerosis: an observational study

BACKGROUND: Skin fibrosis is a hallmark feature of systemic sclerosis. Skin biopsy transcriptomics and blister fluid proteomics give insight into the local environment of the skin. We have integrated these modalities with the aim of developing a surrogate for the modified Rodnan skin score (mRSS), u...

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Detalles Bibliográficos
Autores principales: Clark, Kristina E N, Csomor, Eszter, Campochiaro, Corrado, Galwey, Nicholas, Nevin, Katherine, Morse, Mary A, Teo, Yee Voan, Freudenberg, Johannes, Ong, Voon H, Derrett-Smith, Emma, Wisniacki, Nicolas, Flint, Shaun M, Denton, Christopher P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669928/
https://www.ncbi.nlm.nih.gov/pubmed/36404995
http://dx.doi.org/10.1016/S2665-9913(22)00094-7