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Temperature- and pH-responsive injectable chitosan hydrogels loaded with doxorubicin and curcumin as long-lasting release platforms for the treatment of solid tumors

The efficacy of treating solid tumors with chemotherapy is primarily hindered by dose-limiting toxicity due to off-target effects and the heterogeneous drug distribution caused by the dense extracellular matrix. The enhanced permeability and retention (EPR) effect within tumors restricts the circula...

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Detalles Bibliográficos
Autores principales:	Li, Na, Lin, Jianjun, Liu, Chunping, Zhang, Qian, Li, Riwang, Wang, Chuang, Zhao, Chaochao, Lu, Lu, Zhou, Changren, Tian, Jinhuan, Ding, Shan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669971/ https://www.ncbi.nlm.nih.gov/pubmed/36406213 http://dx.doi.org/10.3389/fbioe.2022.1043939

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