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Analysis of insertions and extensions in the functional evolution of the ribonucleotide reductase family

Ribonucleotide reductases (RNRs) are used by all free‐living organisms and many viruses to catalyze an essential step in the de novo biosynthesis of DNA precursors. RNRs are remarkably diverse by primary sequence and cofactor requirement, while sharing a conserved fold and radical‐based mechanism fo...

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Detalles Bibliográficos
Autores principales: Burnim, Audrey A., Xu, Da, Spence, Matthew A., Jackson, Colin J., Ando, Nozomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9669993/
https://www.ncbi.nlm.nih.gov/pubmed/36307939
http://dx.doi.org/10.1002/pro.4483

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