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Increased stromal PFKFB3-mediated glycolysis in inflammatory bowel disease contributes to intestinal inflammation

Inflammatory bowel disease (IBD) is a chronic relapsing inflammation of the intestinal tract with currently not well-understood pathogenesis. In addition to the involvement of immune cells, increasing studies show an important role for fibroblasts in the pathogenesis of IBD. Previous work showed tha...

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Detalles Bibliográficos
Autores principales: Zhou, Zhou, Plug, Leonie G., Patente, Thiago A., de Jonge-Muller, Eveline S. M., Elmagd, Amir Abou, van der Meulen-de Jong, Andrea E., Everts, Bart, Barnhoorn, Marieke C., Hawinkels, Lukas J. A. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670190/
https://www.ncbi.nlm.nih.gov/pubmed/36405760
http://dx.doi.org/10.3389/fimmu.2022.966067