Daphnoretin relieves IL-1β-mediated chondrocytes apoptosis via repressing endoplasmic reticulum stress and NLRP3 inflammasome

BACKGROUND: Osteoarthritis (OA), mainly caused by severe joint degeneration, is often accompanied by joint pain and dysfunction syndrome. Inflammatory mediators and apoptosis play key roles in the evolution of OA. It is reported that daphnoretin has significant antiviral and anti-tumor values. The p...

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Detalles Bibliográficos
Autores principales: Zhou, Jianbo, Wang, Qinzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670399/
https://www.ncbi.nlm.nih.gov/pubmed/36384642
http://dx.doi.org/10.1186/s13018-022-03316-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670399/
https://www.ncbi.nlm.nih.gov/pubmed/36384642
http://dx.doi.org/10.1186/s13018-022-03316-w

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