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Modeling and cleaning RNA-seq data significantly improve detection of differentially expressed genes

BACKGROUND: RNA-seq has become a standard technology to quantify mRNA. The measured values usually vary by several orders of magnitude, and while the detection of differences at high values is statistically well grounded, the significance of the differences for rare mRNAs can be weakened by the pres...

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Detalles Bibliográficos
Autores principales:	Deyneko, Igor V., Mustafaev, Orkhan N., Tyurin, Alexander А., Zhukova, Ksenya V., Varzari, Alexander, Goldenkova-Pavlova, Irina V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Software
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670425/ https://www.ncbi.nlm.nih.gov/pubmed/36384457 http://dx.doi.org/10.1186/s12859-022-05023-z

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