Antioxidant PDA-PEG nanoparticles alleviate early osteoarthritis by inhibiting osteoclastogenesis and angiogenesis in subchondral bone

Accumulating evidence suggests that osteoclastogenesis and angiogenesis in subchondral bone are critical destructive factors in the initiation and progression of osteoarthritis (OA). Herein, methoxypolyethylene glycol amine (mPEG-NH(2)) modified polydopamine nanoparticles (PDA-PEG NPs) were synthesi...

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Detalles Bibliográficos
Autores principales: Wu, Zhikai, Yuan, Kai, Zhang, Qian, Guo, Jiong Jiong, Yang, Huilin, Zhou, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670483/
https://www.ncbi.nlm.nih.gov/pubmed/36384720
http://dx.doi.org/10.1186/s12951-022-01697-y

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