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Inhibition of Phosphodiesterase 2 Ameliorates Post-Traumatic Stress–Induced Alcohol Intake Disorder by Regulating cAMP/cGMP Signaling

BACKGROUND: Post-traumatic stress disorder (PTSD) is the prevalent psychiatric disorder that induces alcohol use disorders (AUD) such as abnormal alcohol intake and anxiety. However, little is known about whether phosphodiesterase 2 (PDE2)-cAMP/cGMP signaling is involved in PTSD-induced AUD. METHODS...

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Detalles Bibliográficos
Autores principales:	Pan, Xiaoyu, Chen, Ling, Shan, Chunyan, Cai, Lisha, Wang, Yue, Chen, Yue, Gu, Ming, Liu, Kaiping, Li, Pihong, Pan, Jianchun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Regular Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670747/ https://www.ncbi.nlm.nih.gov/pubmed/36124735 http://dx.doi.org/10.1093/ijnp/pyac064

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