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Novel kinome profiling technology reveals drug treatment is patient and 2D/3D model dependent in glioblastoma

Glioblastoma is the deadliest brain cancer. One of the main reasons for poor outcome resides in therapy resistance, which adds additional challenges in finding an effective treatment. Small protein kinase inhibitors are molecules that have become widely studied for cancer treatments, including gliob...

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Detalles Bibliográficos
Autores principales: Fabro, Federica, Kannegieter, Nynke M., de Graaf, Erik L., Queiroz, Karla, Lamfers, Martine L. M., Ressa, Anna, Leenstra, Sieger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670801/
https://www.ncbi.nlm.nih.gov/pubmed/36408180
http://dx.doi.org/10.3389/fonc.2022.1012236