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PFAS and Precursor Bioaccumulation in Freshwater Recreational Fish: Implications for Fish Advisories

[Image: see text] Per- and polyfluoroalkyl substances (PFAS) are a diverse class of fluorinated anthropogenic chemicals that include perfluoroalkyl acids (PFAA), which are widely used in modern commerce. Many products and environmental samples contain abundant precursors that can degrade into termin...

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Autores principales: Pickard, Heidi M., Ruyle, Bridger J., Thackray, Colin P., Chovancova, Adela, Dassuncao, Clifton, Becanova, Jitka, Vojta, Simon, Lohmann, Rainer, Sunderland, Elsie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670858/
https://www.ncbi.nlm.nih.gov/pubmed/36280234
http://dx.doi.org/10.1021/acs.est.2c03734
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author Pickard, Heidi M.
Ruyle, Bridger J.
Thackray, Colin P.
Chovancova, Adela
Dassuncao, Clifton
Becanova, Jitka
Vojta, Simon
Lohmann, Rainer
Sunderland, Elsie M.
author_facet Pickard, Heidi M.
Ruyle, Bridger J.
Thackray, Colin P.
Chovancova, Adela
Dassuncao, Clifton
Becanova, Jitka
Vojta, Simon
Lohmann, Rainer
Sunderland, Elsie M.
author_sort Pickard, Heidi M.
collection PubMed
description [Image: see text] Per- and polyfluoroalkyl substances (PFAS) are a diverse class of fluorinated anthropogenic chemicals that include perfluoroalkyl acids (PFAA), which are widely used in modern commerce. Many products and environmental samples contain abundant precursors that can degrade into terminal PFAA associated with adverse health effects. Fish consumption is an important dietary exposure source for PFAS that bioaccumulate in food webs. However, little is known about bioaccumulation of PFAA precursors. Here, we identify and quantify PFAS in recreational fish species collected from surface waters across New Hampshire, US, using a toolbox of analytical methods. Targeted analysis of paired water and tissue samples suggests that many precursors below detection in water have a higher bioaccumulation potential than their terminal PFAA. Perfluorobutane sulfonamide (FBSA), a short-chain precursor produced by electrochemical fluorination, was detected in all fish samples analyzed for this compound. The total oxidizable precursor assay interpreted using Bayesian inference revealed fish muscle tissue contained additional, short-chain precursors in high concentration samples. Suspect screening analysis indicated these were perfluoroalkyl sulfonamide precursors with three and five perfluorinated carbons. Fish consumption advisories are primarily being developed for perfluorooctane sulfonate (PFOS), but this work reinforces the need for risk evaluations to consider additional bioaccumulative PFAS, including perfluoroalkyl sulfonamide precursors.
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spelling pubmed-96708582022-11-18 PFAS and Precursor Bioaccumulation in Freshwater Recreational Fish: Implications for Fish Advisories Pickard, Heidi M. Ruyle, Bridger J. Thackray, Colin P. Chovancova, Adela Dassuncao, Clifton Becanova, Jitka Vojta, Simon Lohmann, Rainer Sunderland, Elsie M. Environ Sci Technol [Image: see text] Per- and polyfluoroalkyl substances (PFAS) are a diverse class of fluorinated anthropogenic chemicals that include perfluoroalkyl acids (PFAA), which are widely used in modern commerce. Many products and environmental samples contain abundant precursors that can degrade into terminal PFAA associated with adverse health effects. Fish consumption is an important dietary exposure source for PFAS that bioaccumulate in food webs. However, little is known about bioaccumulation of PFAA precursors. Here, we identify and quantify PFAS in recreational fish species collected from surface waters across New Hampshire, US, using a toolbox of analytical methods. Targeted analysis of paired water and tissue samples suggests that many precursors below detection in water have a higher bioaccumulation potential than their terminal PFAA. Perfluorobutane sulfonamide (FBSA), a short-chain precursor produced by electrochemical fluorination, was detected in all fish samples analyzed for this compound. The total oxidizable precursor assay interpreted using Bayesian inference revealed fish muscle tissue contained additional, short-chain precursors in high concentration samples. Suspect screening analysis indicated these were perfluoroalkyl sulfonamide precursors with three and five perfluorinated carbons. Fish consumption advisories are primarily being developed for perfluorooctane sulfonate (PFOS), but this work reinforces the need for risk evaluations to consider additional bioaccumulative PFAS, including perfluoroalkyl sulfonamide precursors. American Chemical Society 2022-10-24 2022-11-15 /pmc/articles/PMC9670858/ /pubmed/36280234 http://dx.doi.org/10.1021/acs.est.2c03734 Text en © 2022 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by-nc-nd/4.0/Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Pickard, Heidi M.
Ruyle, Bridger J.
Thackray, Colin P.
Chovancova, Adela
Dassuncao, Clifton
Becanova, Jitka
Vojta, Simon
Lohmann, Rainer
Sunderland, Elsie M.
PFAS and Precursor Bioaccumulation in Freshwater Recreational Fish: Implications for Fish Advisories
title PFAS and Precursor Bioaccumulation in Freshwater Recreational Fish: Implications for Fish Advisories
title_full PFAS and Precursor Bioaccumulation in Freshwater Recreational Fish: Implications for Fish Advisories
title_fullStr PFAS and Precursor Bioaccumulation in Freshwater Recreational Fish: Implications for Fish Advisories
title_full_unstemmed PFAS and Precursor Bioaccumulation in Freshwater Recreational Fish: Implications for Fish Advisories
title_short PFAS and Precursor Bioaccumulation in Freshwater Recreational Fish: Implications for Fish Advisories
title_sort pfas and precursor bioaccumulation in freshwater recreational fish: implications for fish advisories
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670858/
https://www.ncbi.nlm.nih.gov/pubmed/36280234
http://dx.doi.org/10.1021/acs.est.2c03734
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