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Activation of distinct antiviral T-cell immunity: A comparison of bi- and trispecific T-cell engager antibodies with a chimeric antigen receptor targeting HBV envelope proteins

Despite the availability of an effective prophylactic vaccine, 820,000 people die annually of hepatitis B virus (HBV)-related liver disease according to WHO. Since current antiviral therapies do not provide a curative treatment for the 296 million HBV carriers around the globe, novel strategies to c...

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Detalles Bibliográficos
Autores principales: Debelec-Butuner, Bilge, Quitt, Oliver, Schreiber, Sophia, Momburg, Frank, Wisskirchen, Karin, Protzer, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670976/
https://www.ncbi.nlm.nih.gov/pubmed/36405686
http://dx.doi.org/10.3389/fimmu.2022.1029214