Cargando…
Activation of distinct antiviral T-cell immunity: A comparison of bi- and trispecific T-cell engager antibodies with a chimeric antigen receptor targeting HBV envelope proteins
Despite the availability of an effective prophylactic vaccine, 820,000 people die annually of hepatitis B virus (HBV)-related liver disease according to WHO. Since current antiviral therapies do not provide a curative treatment for the 296 million HBV carriers around the globe, novel strategies to c...
Autores principales: | Debelec-Butuner, Bilge, Quitt, Oliver, Schreiber, Sophia, Momburg, Frank, Wisskirchen, Karin, Protzer, Ulrike |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9670976/ https://www.ncbi.nlm.nih.gov/pubmed/36405686 http://dx.doi.org/10.3389/fimmu.2022.1029214 |
Ejemplares similares
-
Bi- and trispecific immune cell engagers for immunotherapy of hematological malignancies
por: Tapia-Galisteo, Antonio, et al.
Publicado: (2023) -
New pharmacological strategies to fight enveloped viruses
por: Wisskirchen, Karin, et al.
Publicado: (2014) -
NKX3.1 Expression
Contributes to Epithelial–Mesenchymal
Transition of Prostate Cancer Cells
por: Saydullaeva, Iroda, et al.
Publicado: (2023) -
Characterization of a library of 20 HBV-specific MHC class II-restricted T cell receptors
por: Schreiber, Sophia, et al.
Publicado: (2021) -
Inflammation contributes to NKX3.1 loss and augments DNA damage but does not alter the DNA damage response via increased SIRT1 expression
por: Debelec-Butuner, Bilge, et al.
Publicado: (2015)