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Mechanisms underlying the therapeutic effects of 4-octyl itaconate in treating sepsis based on network pharmacology and molecular docking

Objective: Through network pharmacology and molecular docking technology, the hub genes, biological functions, and signaling pathways of 4-Octyl itaconate (4-OI) against sepsis were revealed. Methods: Pathological targets of sepsis were screened using GeneCards and GEO databases. Similarly, the phar...

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Detalles Bibliográficos
Autores principales:	Chen, Maolin, Su, Wenxing, Chen, Fangling, Lai, Tianlun, Liu, Yilun, Yu, Daojiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671214/ https://www.ncbi.nlm.nih.gov/pubmed/36406124 http://dx.doi.org/10.3389/fgene.2022.1056405

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