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Case analysis of early-onset Alzheimer's disease associated with TBK1 p.Tyr235Phe gene mutation

TANK1-binding kinase 1 (TBK1) is mainly involved in the regulation of various cellular pathways through the autophagic lysosomal system, and the loss of function or hypofunction caused by TBK1 gene mutation mainly leads to frontotemporal lobar degeneration (FTLD), amyotrophic lateral sclerosis (ALS)...

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Detalles Bibliográficos
Autores principales:	Li, Pan, Y, Yuanyuan, Cai, Hao, Zhang, Huihong, Zhou, Yuying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671219/ https://www.ncbi.nlm.nih.gov/pubmed/36408501 http://dx.doi.org/10.3389/fneur.2022.993399

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