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A novel function for the sperm adhesion protein IZUMO1 in cell–cell fusion

Mammalian sperm–egg adhesion depends on the trans-interaction between the sperm-specific type I glycoprotein IZUMO1 and its oocyte-specific GPI-anchored receptor JUNO. However, the mechanisms and proteins (fusogens) that mediate the following step of gamete fusion remain unknown. Using live imaging...

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Detalles Bibliográficos
Autores principales:	Brukman, Nicolas G., Nakajima, Kohdai P., Valansi, Clari, Flyak, Kateryna, Li, Xiaohui, Higashiyama, Tetsuya, Podbilewicz, Benjamin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2022
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671554/ https://www.ncbi.nlm.nih.gov/pubmed/36394541 http://dx.doi.org/10.1083/jcb.202207147

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