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Effect of tocilizumab on ischemia-reperfusion-induced oxido-inflammatory renal damage and dysfunction in rats

Ischemia-reperfusion-induced (I/R) renal damage is a pathogenic process that starts with ischemia, then progresses through oxidative stress and inflammation. Tocilizumab (TCZ), a recombinant human monoclonal antibody produced against the IL-6 receptor, will be tested against renal I/R injury. TCZ is...

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Detalles Bibliográficos
Autores principales: Erdem, Kezban Tuna Ozkaloglu, Bedir, Zehra, Kuyrukluyildiz, Ufuk, Tas, Hakan Gokalp, Suleyman, Zeynep, Bulut, Seval, Mendil, Ali Sefa, Sarigul, Cengiz, Unver, Edhem, Suleyman, Halis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671765/
https://www.ncbi.nlm.nih.gov/pubmed/35781445
http://dx.doi.org/10.1538/expanim.22-0034