A novel model mouse for type 2 diabetes mellitus with early onset and persistent hyperglycemia

Various mouse models of type 2 diabetes have been established, but few of these show early onset and persistent hyperglycemia. We have established a congenic mouse strain (NSY.B6-Tyr(+),A(y)) in which a spontaneous mutation of the agouti yellow (A(y)) gene, which causes obesity by hyperphagia, was i...

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Detalles Bibliográficos
Autores principales: Ohno, Tamio, Miyasaka, Yuki, Yoshida, Kanta, Kobayashi, Misato, Horio, Fumihiko, Yokoi, Norihide, Mizuno, Masashi, Ikegami, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2022
Materias:
Original
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671770/
https://www.ncbi.nlm.nih.gov/pubmed/35896366
http://dx.doi.org/10.1538/expanim.22-0061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671770/
https://www.ncbi.nlm.nih.gov/pubmed/35896366
http://dx.doi.org/10.1538/expanim.22-0061

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