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A novel model mouse for type 2 diabetes mellitus with early onset and persistent hyperglycemia
Various mouse models of type 2 diabetes have been established, but few of these show early onset and persistent hyperglycemia. We have established a congenic mouse strain (NSY.B6-Tyr(+),A(y)) in which a spontaneous mutation of the agouti yellow (A(y)) gene, which causes obesity by hyperphagia, was i...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Japanese Association for Laboratory Animal Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9671770/ https://www.ncbi.nlm.nih.gov/pubmed/35896366 http://dx.doi.org/10.1538/expanim.22-0061 |